Solubility Enhancement of Etoricoxib by Cosolvency Approach

Table 1

Solubility profile of etoricoxib in water, PEG 400, PG, and glycerin at room temperature.

Solvent	Dielectric constant	Solubility of etoricoxib (mg/mL) (Mean ± S.D., 𝑛=3)
Water	78.36	0.0767±0.0018
PEG 400	12.40	2.1918±0.0828
PG	32.00	1.6657±0.0482
Glycerin	42.50	0.8488±0.0196