Research Article

Conservation, Compensation, and Evolution of N-Linked Glycans in the HIV-1 Group M Subtypes and Circulating Recombinant Forms

Table 2

2G12 conservation percentage of sequences representing each of the subtypes/CRFs exhibiting glycosylation at all positions in the conserved 2G12 core epitope (295N, 332N, and 392N) and the core epitope with peripheral glycans that have been suggested to be involved in 2G12 binding (339N, 386N, and 448N).

Subtype/CRFCore epitopeCore + peripheral glycans

A33%27%
B61%36%
C11%5%
D35%23%
CRF01_AE1%1%
CRF02_AG60%35%