Table of Contents
ISRN Oncology
Volume 2012, Article ID 825258, 7 pages
http://dx.doi.org/10.5402/2012/825258
Clinical Study

Prognostic Factors and Recurrence in Breast Cancer: Experience at the National Cancer Institute of Mexico

1Breast Cancer Department, National Cancer Institute of Mexico, 14080 Tlalpan, DF, Mexico
2National Cancer Institute of Mexico, 14080 Tlalpan, DF, Mexico
3Department of Critical Care Medicine, National Cancer Institute of Mexico, 14080 Tlalpan, DF, Mexico

Received 16 March 2012; Accepted 28 April 2012

Academic Editors: R. Nahta and L.-M. Sun

Copyright © 2012 A. Stankov et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

The purpose of this study was to analyze the prognostic and predictive factors that relate to locoregional or distant recurrences in breast cancer patients who have been treated at the National Cancer Institute of Mexico. Multivariate, time-dependent Cox regression analyses indicate that the pN status (positive versus negative lymph node; 𝑃 = 0 . 0 0 3 ; HR (hazard ratio), 3.47; CI (confidence interval), 1.52–7.91) and the pathological complete response of the patient to neoadjuvant chemotherapy (yes versus no; 𝑃 = 0 . 0 6 1 ; HR, 0.38; CI, 0.14–1.04) were important prognostic factors for recurrence.