Review Article

The Multifaceted Granulosa Cell Tumours—Myths and Realities: A Review

Figure 4

(a) CT scan abdomen shows a large heterogenous pelvic mass ( ), solid and cystic. Abscess, ?GIST extracolonic mass, ?Ovarian tumour. (b) Photomicrograph of haematoxylin and eosin-stained slide at low power (lens objective x4) shows the presence of two distinct histological phenotypes: a) diffuse cords of neoplastic cells in the upper left-hand corner (+) and b) neoplastic glands with “dirty” necrosis in the lower right-hand corner ( ). (c) Photomicrograph of immunohistochemical staining shows diffuse-positive staining to inhibin A in the solid cords of neoplastic cells (+) with negative staining in the adjacent glandular component ( ). (d) Photomicrograph of immunohistochemical staining shows diffuse positive staining to CK20 in the glandular component ( ) with negative staining in the adjacent solid cords of neoplastic cells (+).
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