Clinical Study

Symptom Distress Associated with Biopsy in Women with Suspect Breast Lesions

Table 1

Descriptive statistics for outcome measures for ALL participants and by diagnostic status* at pre- ( 𝑇 1 ) and post-biopsy ( 𝑇 2 ) visits.

Outcome measure VisitAll participantsBC positive participantsBC negative participants
Mean  Β±  SDMean  Β±  SDMean  Β±  SD

Anxiety subscale of HADS 𝑇 1 8.53  Β±  3.63 (n = 38)9.00  Β±  2.37 (n = 11)8.33  Β±  4.06 (n = 27)
𝑇 2 7.61  Β±  3.49 (n = 38)8.46  Β±  2.88 (n = 11)7.26  Β±  3.71 (n = 27)
Depressive subscale of HADS 𝑇 1 4.66  Β±  3.57 (n = 38)3.91  Β±  3.08 (n = 11)4.96  Β±  3.77 (n = 27)
𝑇 2 4.08  Β±  4.05 (n = 38)3.45  Β±  3.59 (n = 11)4.33  Β±  4.26 (n = 27)
Fatigue (BFI) 𝑇 1 2.78  Β±  2.17 (n = 47)2.79  Β±  1.34 (n = 15)2.77  Β±  2.49 (n = 32)
𝑇 2 2.68  Β±  1.99 (n = 47)2.62  Β±  1.34 (n = 15)2.70  Β±  2.25 (n = 32)
Fatigue level (BFI) 𝑇 1 1.28  Β±  0.50 (n = 47)1.20  Β±  0.41 (n = 15)1.31  Β±  0.54 (n = 32)
𝑇 2 1.26  Β±  0.49 (n = 47)1.13  Β±  0.35 (n = 15)1.31  Β±  0.54 (n = 32)
Sleep (PSQI) 𝑇 1 7.13  Β±  3.59 (n = 47)6.60  Β±  2.64 (n = 15)7.38  Β±  3.97 (n = 32)
𝑇 2 7.15  Β±  3.72 (n = 46)6.86  Β±  3.94 (n = 14)7.28  Β±  3.67 (n = 32)
PANAS positive subscale 𝑇 1 33.17  Β±  9.58 (n = 47)33.60  Β±  6.48 (n = 15)32.97  Β±  10.83 (n = 32)
𝑇 2 33.39  Β±  9.30 (n = 46)31.57  Β±  7.17 (n = 14)34.19  Β±  10.09 (n = 32)
PANAS negative subscale 𝑇 1 21.72  Β±  7.75 (n = 47)21.73  Β±  7.75 (n = 15)21.72  Β±  7.88 (n = 32)
𝑇 2 20.83  Β±  7.84 (n = 46)23.21  Β±  8.41 (n = 14)19.78  Β±  7.48 (n = 32)
Quality of life (EORTC) 𝑇 1 74.82  Β±  18.91 (n = 47)77.78  Β±  12.86 (n = 15)73.44  Β±  21.21 (n = 32)
𝑇 2 71.28  Β±  21.69 (n = 47)69.44  Β±  15.00 (n = 15)72.14  Β±  24.37 (n = 32)
Modified social support (MSSS) 𝑇 1 76.56  Β±  22.63 (n = 46)79.58  Β±  17.63 (n = 14)75.24  Β±  24.64 (n = 32)
𝑇 2 77.52  Β±  26.81 (n = 47)89.57  Β±  16.77 (n = 15)71.88  Β±  28.92 (n = 32)
C-reactive protein (CRP)** 𝑇 1 7248.06  Β±  7823.91 (n = 47)6601.80  Β±  8583.84 (n = 15)7551.00  Β±  7567.07 (n = 32)
𝑇 2 8358.26  Β±  8597.71 (n = 47)9696.07  Β±  11426.52 (n = 15)7731.16  Β±  7032.20 (n=32)
Interleukin-6 (IL-6)** 𝑇 1 348.59  Β±  616.14 (n = 34)273.84  Β±  472.48 (n = 11)384.34  Β±  681.06 (n = 23)
𝑇 2 296.29  Β±  556.48 (n = 39)213.49  Β±  443.79 (n = 14)342.66  Β±  614.32 (n = 25)

BC: breast cancer, *Diagnostic status (BC+ or BCβˆ’) was determined after biopsy. It is important to note that participants are not aware of their BC status at the first ( 𝑇 1 ) visit, **Marker on inflammation.