Figure 4: Gastrointestinal and genitor-urinary adverse effect profiles. The frequency of reported adverse effects for each drug is given according to the color key. The categories that included a spectrum of symptoms are as follows: change in liver enzymes (transaminase, bilirubin, hepatic failure, hepatic encephalopathy or coma, hepatitis); urinary symptoms (abnormal urine, enuresis, dysuria, pyuria, hematuria, difficulty urinating, nocturia, polyuria, incontinence, retention, change in frequency); change in kidney function (hyponatremia, acute renal failure).