Method Development and Validation for the Simultaneous Determination of Fexofenadine Hydrochloride and Montelukast Sodium in Drug Formulation Using Normal Phase High-Performance Thin-Layer Chromatography

Table 1

Linear regression data for calibration curves (𝑛=6).

Parameters	FEX	MTKT
Linearity range	2400–10800 ng spot^−1	200–900 ng spot^−1
Slope ± Standard error	1.651±0.01	6.900±0.04
Intercept ± Standard error	1019±90.27	−16.12±25.18
Confidence limit of slope^a	1.620 to 1.682	6.796 to 7.003
Confidence limit of intercept^a	798.1 to 1240	−77.73 to 45.49
𝑟^2	0.9996	0.9998
Sy.x^b	98.19	27.38
P value^c	<0.0001	<0.0001

^a95% confidence intervals.
^bStandard deviation of residuals from line.
^cP value is < 0.0001, considered extremely significant.