Research Article
Synthesis, Urease Inhibition, Antioxidant, Antibacterial, and Molecular Docking Studies of 1,3,4-Oxadiazole Derivatives
Table 2
Antibacterial activity of 1,3,4-oxadiazoles derivatives by micro dilution method (MICa values μg/mL).
| Compound | E. coli | B. subtilus | S. aureus | S. flexneri |
| 4a | 0.313 | 0.156 | 1.25 | 0.313 | 4b | 0.625 | 0.313 | 0.156 | 0.313 | 4c | 2.50 | 0.156 | 0.625 | 0.156 | 4e | 0.156 | 0.625 | 0.313 | 0.313 | 4f | 0.313 | 0.156 | 0.156 | 1.25 | 4g | 0.156 | 0.625 | 2.50 | 0.313 | 4h | 1.25 | 0.156 | 0.625 | 0.156 | 4i | 0.156 | 0.625 | 0.313 | 0.313 | 4j | 0.313 | 1.25 | 0.313 | 0.156 | 4k | 0.156 | 0.313 | 0.156 | 0.156 | 4l | 0.313 | 2.50 | 0.625 | 0.156 | 4m | 0.625 | 0.156 | 1.25 | 0.313 | 4n | 0.625 | 0.156 | 0.156 | 0.156 | 4o | 0.313 | 0.625 | 2.50 | 0.156 | 4r | 1.25 | 0.313 | 0.156 | 0.313 | Ciprofloxacin | 0.156 | 0.625 | 0.156 | 0.31 |
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aValues are the average of three reading.
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