VEGF Is Involved in the Increase of Dermal Microvascular Permeability Induced by Tryptase

<table>Effect of tryptase on the VEGF, Flt-1, and Flk-1 mRNA levels in HDMECs. Different concentrations of tryptase (0, 1, and 10 nmol/L) were added into HDMECs for 6 h. The mRNA levels of VEGF (a), Flt-1 (b), and Flk-1 (c) were determined by Real-time RT-PCR and normalized to GAPDH. The heparin control was also analyzed. <svg height="15.4375" id="M21" style="vertical-align:-3.13504pt" version="1.1" viewbox="0 0 65.099998 15.4375" width="65.099998" xmlns="http://www.w3.org/2000/svg">
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<tspan style="font-size: 8.75px; " x="0" y="0">∗</tspan>
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<tspan style="font-size: 12.50px; " x="0" y="0">𝑃</tspan>
<tspan style="font-size: 12.50px; " x="10.9" y="-0.95999998">&lt;</tspan>
<tspan style="font-size: 12.50px; " x="22.927885" y="-0.95999998">0</tspan>
<tspan style="font-size: 12.50px; " x="29.179386" y="-0.95999998">.</tspan>
<tspan style="font-size: 12.50px; " x="32.305138" y="-0.95999998">0</tspan>
<tspan style="font-size: 12.50px; " x="38.556637" y="-0.95999998">5</tspan>
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</svg> compared to the group of heparin control.</table>

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Figure 3

Figure 3: VEGF Is Involved in the Increase of Dermal Microvascular Permeability Induced by Tryptase 