Evaluation of the Periodontal Status in Acromegalic Patients: A Comparative Study

Table 2

Characteristics for acromegaly patients and healthy SHIP-1 subjects.

Variable	Acromegaly patients	Healthy SHIP-1 subjects	𝑃^∗
𝑁	32	128
Age (years)	58 (48; 64)	58 (48; 64)	0.99
Male gender	50.0%	50.0%	1.00
School education
<10 years	31.3%	32.0%
10 years	50.0%	48.4%
>10 years	18.7%	19.5%	0.99
Smoking status
Never smoker	40.6%	39.1%
Former smoker	34.4%	40.6%
Current smoker	25.0%	20.3%	0.77
Diabetes mellitus**	18.8%	7.0%	0.04
Presence of metabolic syndrome	34.4%	36.7%	0.81
Body Mass Index (kg/m^2)	28.6 (25.4; 32.7)	28.3 (25.1; 31.1)	0.39
Waist circumference (cm)	92 (86; 104)	95 (86; 102)	0.96
Systolic blood pressure (mmHg)	127 (119; 138)	134 (123; 143)	0.16
Diastolic blood pressure (mmHg)	83 (75; 88)	82 (75; 90)	0.76
Serum glucose (mmol/L)^#	5.4 (5.0; 6.8)	5.2 (4.8; 5.8)	0.26
Serum triglycerides (mmol/L)^#	1.5 (1.0; 2.2)	1.6 (1.1; 2.3)	0.49
Serum HDL-C (mmol/L)^#	1.3 (1.1; 1.6)	1.1 (0.88; 1.4)	0.004
Serum LDL-C (mmol/L)^#	3.4 (3.0; 4.2)	3.7 (3.0; 4.5)	0.55
Hormone replacement therapy	18.8%	0.0%	<0.001
IGF-I (ng/mL)	153 (107; 2012)	138 (112; 173)	0.19
IGFBP-3 (ng/mL)	4880 (3840; 5595)	4085 (3580; 4625)	0.004
IGF-I/IGFBP-3	0.035 (0.028; 0.041)	0.034 (0.029; 0.042)	0.74
Mean CAL (mm)	2.28 (1.35; 3.67)	2.19 (1.02; 3.39)	0.43
Mean PD (mm)	2.30 (1.92; 2.78)	2.10 (1.87; 2.58)	0.42
Number of missing teeth	7 (2; 11)	6 (2; 12)	0.65
Missing teeth ≥10	28.1%	30.5%	0.80

Data are presented as percentages or median (25% quantile; 75% quantile).
IGF-I: insulin-like growth factor-1; 𝑁: number; HDL-C: high-density lipoprotein cholesterol; LDL-C: low-density lipoprotein cholesterol; CAL: clinical attachment loss; PD: probing depth.
*Chi-square test (categorical data) or Mann-Whitney- 𝑈 test (continuous data).
**Self-reported physician’s diagnosis or antidiabetic treatment (ATC code A10).
^#Nonfasting blood samples.