Clinical Study

Ovarian Reserve in Women Treated for Acute Lymphocytic Leukemia or Acute Myeloid Leukemia with Chemotherapy, but Not Stem Cell Transplantation

Table 2

Timing of chemotherapy, hormonal treatments, and menstrual change.

SubjectAgeTime since chemotherapy (years)Time between menarche and chemotherapy (years)Menstrual change during chemotherapyTime to return of menses (months)Duration of COC (months)Duration of GnRH agonist (months)Menstrual change after chemotherapy

1393.723Stopped9–120UnknownLighter
2334.018Stopped<10.53Restarted and returned to normal
3332.418Stopped>12031Restarted and returned to normal
4270.514More frequent<1246Lighter
5251.812Stopped6–9024Lighter

COC: combined oral contraception. GnRH agonist: gonadotropin releasing hormone agonist.