Table of Contents
ISRN Obesity
Volume 2012, Article ID 960427, 9 pages
http://dx.doi.org/10.5402/2012/960427
Research Article

Moderate Weight Loss Decreases Oxidative Stress and Increases Antioxidant Status in Patients with Metabolic Syndrome

I Clinica Medica, Dipartimento di Medicina Interna e Specialità Mediche, La Sapienza Università di Roma, Policlinico Umberto I, Viale del Policlinico 155, 00161 Roma, Italy

Received 8 October 2012; Accepted 24 October 2012

Academic Editors: M. Binks, D. Micic, and J. Zempleni

Copyright © 2012 Maria Del Ben et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. J. I. Cleeman, “Executive summary of the third report of the National Cholesterol Education Program (NCEP) expert panel on detection, evaluation, and treatment of high blood cholesterol in adults (adult treatment panel III),” Journal of the American Medical Association, vol. 285, no. 19, pp. 2486–2497, 2001. View at Google Scholar · View at Scopus
  2. J. P. Després, I. Lemieux, J. Bergeron et al., “Abdominal obesity and the metabolic syndrome: contribution to global cardiometabolic risk,” Arteriosclerosis, Thrombosis, and Vascular Biology, vol. 28, no. 6, pp. 1039–1049, 2008. View at Publisher · View at Google Scholar · View at Scopus
  3. S. M. Grundy, “Metabolic syndrome pandemic,” Arteriosclerosis, Thrombosis, and Vascular Biology, vol. 28, no. 4, pp. 629–636, 2008. View at Publisher · View at Google Scholar
  4. K. G. M. M. Alberti, R. H. Eckel, S. M. Grundy et al., “Harmonizing the metabolic syndrome: a joint interim statement of the international diabetes federation task force on epidemiology and prevention; National heart, lung, and blood institute; American heart association; World heart federation; International atherosclerosis society; And international association for the study of obesity,” Circulation, vol. 120, no. 16, pp. 1640–1645, 2009. View at Publisher · View at Google Scholar · View at Scopus
  5. S. Mottillo, K. B. Filion, J. Genest et al., “The metabolic syndrome and cardiovascular risk: a systematic review and meta-analysis,” Journal of the American College of Cardiology, vol. 56, no. 14, pp. 1113–1132, 2010. View at Publisher · View at Google Scholar · View at Scopus
  6. C. Lorenzo, K. Williams, K. J. Hunt, and S. M. Haffner, “The National Cholesterol Education Program-Adult Treatment Panel III, International Diabetes Federation, and World Health Organization definitions of the metabolic syndrome as predictors of incident cardiovascular disease and diabetes,” Diabetes Care, vol. 30, no. 1, pp. 8–13, 2007. View at Publisher · View at Google Scholar · View at Scopus
  7. G. Riccardi and A. A. Rivellese, “Dietary treatment of the metabolic syndrome—the optimal diet,” British Journal of Nutrition, vol. 83, supplement 1, pp. S143–S148, 2000. View at Google Scholar · View at Scopus
  8. J. F. Keaney, M. G. Larson, R. S. Vasan et al., “Obesity and systemic oxidative stress: clinical correlates of oxidative stress in the Framingham study,” Arteriosclerosis, Thrombosis, and Vascular Biology, vol. 23, no. 3, pp. 434–439, 2003. View at Publisher · View at Google Scholar · View at Scopus
  9. H. K. Vincent, K. E. Innes, and K. R. Vincent, “Oxidative stress and potential interventions to reduce oxidative stress in overweight and obesity,” Diabetes, Obesity and Metabolism, vol. 9, no. 6, pp. 813–839, 2007. View at Publisher · View at Google Scholar · View at Scopus
  10. I. Karamouzis, P. Pervanidou, R. Berardelli et al., “Enhanced oxidative stress and platelet activation combined with reduced antioxidant capacity in obese prepubertal and adolescent girls with full or partial metabolic syndrome,” Hormone and Metabolic Research, vol. 43, no. 9, pp. 607–613, 2011. View at Publisher · View at Google Scholar
  11. J. V. Higdon and B. Frei, “Obesity and oxidative stress: a direct link to CVD?” Arteriosclerosis, Thrombosis, and Vascular Biology, vol. 23, no. 3, pp. 365–367, 2003. View at Publisher · View at Google Scholar · View at Scopus
  12. F. Angelico, L. Loffredo, P. Pignatelli et al., “Weight loss is associated with improved endothelial dysfunction via NOX2-generated oxidative stress down-regulation in patients with the metabolic syndrome,” Internal and Emergency Medicine, vol. 7, no. 3, pp. 219–227, 2012. View at Publisher · View at Google Scholar · View at Scopus
  13. R. Brigelius-Flohé and M. G. Traber, “Vitamin E: function and metabolism,” The FASEB Journal, vol. 13, no. 10, pp. 1145–1155, 1999. View at Google Scholar · View at Scopus
  14. US Department of Agriculture, Agricultural Research Service, “USDA National Nutrient Database for Standard Reference,” Release 23, 2010.
  15. I. Myara, C. Alamowitch, O. Michel et al., “Lipoprotein oxidation and plasma vitamin E in nondiabetic normotensive obese patients,” Obesity Research, vol. 11, no. 1, pp. 112–120, 2003. View at Google Scholar · View at Scopus
  16. I. Mehmetoglu, F. H. Yerlikaya, and S. Kurban, “Correlation between vitamin A, E, coenzyme Q10 and degree of insulin resistance in obese and non-obese subjects,” Journal of Clinical Biochemistry and Nutrition, vol. 49, no. 3, pp. 159–163, 2011. View at Publisher · View at Google Scholar
  17. P. Wallström, E. Wirfält, P. H. Lahmann, B. Gullberg, L. Janzon, and G. Berglund, “Serum concentrations of β-carotene and α-tocopherol are associated with diet, smoking, and general and central adiposity,” American Journal of Clinical Nutrition, vol. 73, no. 4, pp. 777–785, 2001. View at Google Scholar · View at Scopus
  18. P. Gascón-Vila, R. Garcia-Closas, L. Serra-Majem et al., “Determinants of the nutritional status of vitamin E in a nonsmoking Mediterranean population. Analysis of the effect of vitamin E intake, alcohol consumption and body mass index on the serum alpha-tocopherol concentration,” European Journal of Clinical Nutrition, vol. 51, no. 11, pp. 723–728, 1997. View at Google Scholar · View at Scopus
  19. E. S. Ford, A. H. Mokdad, W. H. Giles, and D. W. Brown, “The metabolic syndrome and antioxidant concentrations: findings from the Third National Health and Nutrition Examination Survey,” Diabetes, vol. 52, no. 9, pp. 2346–2352, 2003. View at Publisher · View at Google Scholar · View at Scopus
  20. M. G. Traber and I. Jialal, “Measurement of lipid-soluble vitamins—further adjustment needed?” The Lancet, vol. 355, no. 9220, pp. 2013–2014, 2000. View at Google Scholar · View at Scopus
  21. Z. Wang, G. Ciabattoni, C. Creminon et al., “Immunological characterization of urinary 8-epi-prostaglandin F2 alpha excretion in man,” Journal of Pharmacology and Experimental Therapeutics, vol. 275, no. 1, pp. 94–100, 1995. View at Google Scholar · View at Scopus
  22. P. Pignatelli, R. Carnevale, R. Cangemi et al., “Atorvastatin inhibits gp91phox circulating levels in patients with hypercholesterolemia,” Arteriosclerosis, Thrombosis, and Vascular Biology, vol. 30, no. 2, pp. 360–367, 2010. View at Publisher · View at Google Scholar · View at Scopus
  23. K. F. Gey, P. Puska, P. Jordan, and U. K. Moser, “Inverse correlation between plasma vitamin E and mortality from ischemic heart disease in cross-cultural epidemiology,” American Journal of Clinical Nutrition, vol. 53, supplement 1, pp. 326S–334S, 1991. View at Google Scholar · View at Scopus
  24. E. Azzini, A. Polito, A. Fumagalli et al., “Mediterranean diet effect: an Italian picture,” Nutrition Journal, vol. 10, article 125, 2011. View at Google Scholar
  25. M. A. Beydoun, M. R. Shroff, X. Chen, H. A. Beydoun, Y. Wang, and A. B. Zonderman, “Serum antioxidant status is associated with metabolic syndrome among U.S. adults in recent national surveys,” Journal of Nutrition, vol. 141, no. 5, pp. 903–913, 2011. View at Publisher · View at Google Scholar · View at Scopus
  26. C. Roberto, P. Pasquale, D. S. Serena et al., “Atorvastatin inhibits oxidative stress via adiponectin-mediated NADPH oxidase down-regulation in hypercholesterolemic patients,” Atherosclerosis, vol. 213, no. 1, pp. 225–234, 2010. View at Publisher · View at Google Scholar · View at Scopus
  27. I. Jialal, S. Devaraj, B. Adams-Huet, X. Chen, and H. Kaur, “Increased cellular and circulating biomarkers of oxidative stress in nascent metabolic syndrome,” The Journal of Clinical Endocrinology & Metabolism, vol. 97, no. 10, pp. E1844–E1850, 2012. View at Publisher · View at Google Scholar
  28. S. Nakanishi, K. Yamane, N. Kamei, H. Nojima, M. Okubo, and N. Kohno, “A protective effect of adiponectin against oxidative stress in Japanese Americans: the association between adiponectin or leptin and urinary isoprostane,” Metabolism: Clinical and Experimental, vol. 54, no. 2, pp. 194–199, 2005. View at Publisher · View at Google Scholar · View at Scopus
  29. K. Park, M. Gross, D. H. Lee et al., “Oxidative stress and insulin resistance: the Coronary Artery Risk Development in Young Adults study,” Diabetes Care, vol. 32, no. 7, pp. 1302–1307, 2009. View at Publisher · View at Google Scholar · View at Scopus
  30. S. Shah, M. Iqbal, J. Karam, M. Salifu, and S. I. McFarlane, “Oxidative stress, glucose metabolism, and the prevention of type 2 diabetes: pathophysiological insights,” Antioxidants and Redox Signaling, vol. 9, no. 7, pp. 911–929, 2007. View at Publisher · View at Google Scholar · View at Scopus
  31. S. Phelan and R. R. Wing, “Prevalence of successful weight loss,” Archives of Internal Medicine, vol. 165, no. 20, p. 2430, 2005. View at Google Scholar · View at Scopus