Moderate Weight Loss Decreases Oxidative Stress and Increases Antioxidant Status in Patients with Metabolic Syndrome
Table 3
Baseline values of some nutritional, anthropometric, and biochemical characteristics of the study participants and changes after 6 months of low-calorie, low-fat diet according to body weight reduction: group A ≥5%; group B <5%.
Variables
Group A
Group B
Between-groups comparison
Body weight reduction ≥5%,
Body weight reduction <5%,
of change
Baseline
6 months
%
Baseline
6 months
%
Difference (95% CI)
value at 6 months
Total energy (Kcal)
***
−23.0
−2.7
−562 (−750 to −374)
<.001
Total fat (g)
***
−33.2
−5.0
−36.8 (−53.1 to −20.5)
<.001
Saturated fat (g)
***
−33.0
−4.5
−10.6 (−16.0 to −5.1)
<.001
Monounsaturated fat (g)
***
−35.0
−5.3
−22.9 (−43.1 to −11.8)
<.001
Polyunsaturated fat (g)
***
−26.2
−1.7
−2.8 (−4.2 to −1.5)
<.001
Oil/seasoning fat (teasp/wk)
§
***
−58.6
−2.5
−81.8 (−108.2 to −55.4)
<.001
Body weight, (kg)
***
−6.8
+0.1
−6.6 (−8.1 to −5.0)
<.001
Urinary 8-isoprostanes (pg/mg creatinine)
**
−39.0
−3.9
−51.3 (−99.0 to −3.6)
.035
sNOX2-dp (pg/mL)
*
−22.2
−8.8
−20.2 (−34.5 to 5.9)
<.01
Adiponectin (ng/mg)
***
+125.5
13.3
+4.8 (3.6 to 6.0)
<.01
Vitamin E (mol)
***
+100.2
+4.3
−95.4 (−150.8 to 41.0)
<.001
Cholesterol (mol)
**
−13.0
−0.1
13.1 (6.7 to 19.6)
<.001
Vitamin E/cholesterol ratio
***
+129.8
+5.4
+4.8 (3.5 to 6.1)
<.001
*
; **; ***, 6 months versus baseline. § versus group B at baseline. Statistical analysis was performed by -test (for between-groups analysis) and paired -test (for within-group analysis).
