International Scholarly Research Notices / 2012 / Article / Tab 3

Research Article

Effects of a Physical Activity Program on Markers of Endothelial Dysfunction, Oxidative Stress, and Metabolic Status in Adolescents with Metabolic Syndrome

Table 3

Baseline markers of inflammation, endothelial dysfunction, and oxidative stress in adolescents.

Women ( 𝑛 = 1 8 )Men ( 𝑛 = 2 0 )
Mean (SD)Mean (SD)
With MetSWithout MetS 𝑃 With MetSWithout MetS 𝑃

Markers of inflammation
 hsCRP0.16 (0.13)0.07 (0.04)0.1000.09 (0.06)0.13 (0.08)0.244
 Fg457 (138)377 (163)0.326438 (177)417 (141)0.793
Markers of endothelial cell dysfunction
 PAI-137.2 (11)27.4 (8.9)0.10239.2 (5.7)38.9 (10)0.937
 tPA5.8 (2.9)3.2 (1.3)0.0664.4 (1.8)4.9 (2.4)0.573
 vWF144 (27)129 (28)0.308146 (26)150 (37)0.753
 FVIII121 (24)112 (32)0.560112 (27)134 (42)0.203
 sVCAM-117.4 (6.1)22.8 (14)0.30726.9 (17)19.9 (5.6)0.374
 P-selectin24.4 (4.7)20.0 (5.3)0.11922.4 (10)24.0 (8.9)0.748
Markers of oxidative stress
 Lpox518 (119)663 (168)0.083605 (223)589 (269)0.893
 SOD341 (237)876 (399)0.008681 (385)510 (709)0.530
 Cat16.8 (13)19.9 (16)0.69915.4 (14)13.4 (8.6)0.746
 Gpox964 (1282)513 (678)0.4512303 (2225)3792 (3869)0.328
 SOD/Gpox + Cat17.8 (13)24.0 (18)0.47516.1 (14)15.1 (11)0.874

hsCRP: high-sensitivity C-reactive protein (mg/dL); Fg: fibrinogen (mg/dL); PAI-1: plasminogen activator inhibitor type 1 (ng/mL); tPA: tissue plasminogen activator (ng/mL); vWF: von Willebrand factor (U/mL); FVIII: factor VIII (%); sVCAM-1: soluble vascular cell adhesion molecule-1 (U/mL); P-selectin (U/mL); Lpox: lipoperoxidation (nMol MDA/gHb); SOD: superoxide dismutase (μMol adrenalin/gHb); Cat: catalase (μMol H2O2/gHb); Gpox: glutathione peroxidase (μMol NADPH/gHb). *Sudent's 𝑡 -test.

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