TY - JOUR A2 - Minin, A. A. A2 - Uphoff, C. C. A2 - Meacci, E. AU - Payushina, Olga V. PY - 2012 DA - 2012/10/23 TI - Hematopoietic Microenvironment in the Fetal Liver: Roles of Different Cell Populations SP - 979480 VL - 2012 AB - Hematopoiesis is the main function of the liver during a considerable period of mammalian prenatal development. Hematopoietic cells of the fetal liver exist in a specific microenvironment that controls their proliferation and differentiation. This microenvironment is created by different cell populations, including epitheliocytes, macrophages, various stromal elements (hepatic stellate cells, fibroblasts, myofibroblasts, vascular smooth muscle and endothelial cells, mesenchymal stromal cells), and also cells undergoing epithelial-to-mesenchymal transition. This paper considers the involvement of these cell types in the regulation of fetal liver hematopoiesis. SN - null UR - https://doi.org/10.5402/2012/979480 DO - 10.5402/2012/979480 JF - ISRN Cell Biology PB - International Scholarly Research Network KW - ER -