Clinical Study

The Effects of Continuous Blood Purification for SIRS/MODS Patients: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

Table 5

IL-6 change.

Study or subgroupCVVHControlStd. mean differenceStd. mean difference
MeanSDTotalMeanSDTotalWeightIV, fixed, 95%CIIV, fixed, 95%CI

1.1.1 after 3 days986765.tab.005
 Liu et al. 2003 [10]2278.58244689.742646.3%−0.28 (−0.84, 0.28)
 Zhang et al. 2008 [15]8.994.593013.439.33053.7%−0.60 (−1.12, −0.08)
Subtotal (95%Cl)5456100.0%−0.45 (−0.83, −0.07)
Heterogeneity: Chi-square = 0.67, df = 1 ( = 0.41); = 0%
Test for overall effect = 2.32 ( = 0.02)
1.1.2 after 7 days
 Liu et al. 2003 [10] 31 78.58 24 32 93.58 2665.0%−0.01 (−0.57, 0.54)
 Zhang et al. 2008 [15] −18.57 4.44 30 −5.34 4.16 3035.0%−3.04 (−3.79, −2.28)
Subtotal (95%Cl)5456100.0%−1.07 (−1.52, −0.62)
Heterogeneity: Chi-square = 39.93, df = 1 ( < 0.00001); = 97%
Test for overall effect: = 4.69 ( < 0.00001)
Test for subgroup differences: Chi-square = 4.28, df = 1 ( = 0.04), = 76.7%