Sicker Patients for Liver Transplantation: Meld, Meld Sodium, and Integrated Meld’s Prognostic Accuracy in the Assessment of Posttransplantation Events at a Single Center from Argentina
Figure 1
AUROC curves analyzing 3 months after liver transplant patient survival. (a) Receiver operating characteristic (ROC) curve for 3 months after transplant survival ranked on the basis of pretransplant MELD score. The -statistic was 0.694 (0.56–0.82); . Best cut-off of sensibility and specificity for MELD is >25. (b) Receiver operating characteristic (ROC) curve for 3 months after transplant survival ranked on the basis of pretransplant MELD sodium 1 score [4]. The -statistic was 0.682 (0.56–0.79); . Best cut-off of sensibility and specificity for MELD Na1 is >30. MELD Na1 : MELD sodium 1 : MELD + 1.59 × (135 – patient’s serum sodium mEq/L). (c) Receiver operating characteristic (ROC) curve for 3 months after transplant survival ranked on the basis of pretransplant MELD sodium 2 score [15]. The -statistic was 0.651 (0.54–0.76); . Best cut-off of sensibility and specificity for MELD Na2 is >27. MELD Na2 : MELD sodium 2 : MELD – Na − [0.025 × MELD × (140 – Na)] + 140. (d) Receiver operating characteristic (ROC) curve for 3 months after transplant survival ranked on the basis of pretransplant MELD sodium 2 score [5]. The -statistic was 0.698 (0.593–0.80); . Best cut-off of sensibility and specificity for iMELD is >47. iMELD: integrated MELD: MELD + (age × 0.3) − (0.7 × Na p) + 100.