Sexually Transmitted Infections and Male Circumcision: A Systematic Review and Meta-Analysis
Table 10
Studies of the association between circumcision status and the prevalence of genital herpes/herpes simplex virus type 2.
Study
Intact +ve/−ve
Circumcised +ve/−ve
Odds ratio
95% confidence interval
Exact odds ratio
Exact confidence interval
Bassett
69/36
125/70
1.07
0.65–1.34
1.0731
0.6348–1.8283
Buvé
136/199
36/96
1.82
1.17–2.83
1.8202
1.1512–2.9206
Cook
49/491
205/2031
0.99
0.70–1.37
0.9887
0.6977–1.3795
Dave
48/4785
11/971
0.89
0.46–1.71
0.8855
0.4514–1.8979
Dickson
19/241
13/162
0.98
0.47–2.04
0.9825
0.4460–2.2295
Donovan
21/94
27/158
1.31
0.70–2.44
1.3061
0.6618–2.5514
Ferris
28/1594
55/2317
0.74
0.47–1.17
0.7401
0.4499–1.1930
Gottlieb
27/295
74/724
0.90
0.56–1.42
0.8956
0.5424–1.4419
Gray
395/160
76/43
1.40
0.92–2.12
1.3961
0.8962–2.1560
Kapiga
3/8
57/138
1.10
0.28–4.30
0.9083
0.1499–3.9591
Laumann
9/1109
22/1427
0.53
0.24–1.15
0.5265
0.2125–1.1955
Lavreys
20/28
32/33
0.74
0.35–1.56
0.7386
0.3237–1.6679
Mallon
8/267
0/82
5.24
0.30–91.81
3.3651
0.5116–[22.1343]*
Mujugira
669/358
760/483
1.19
1.00–1.41
1.1875
0.9966–1.4156
Mwandi
396/546
1320/4355
2.39
2.07–2.76
2.3925
2.0671–2.7677
Ng’ayo
146/86
14/4
0.49
0.15–1.52
0.4863
0.1129–1.6142
Obasi
25/77
5/25
1.62
0.56–4.69
1.6179
0.5292–5.9872
Parker
60/530
44/685
1.76
1.18–2.64
1.7617
1.1535–2.7079
Reynolds
178/1096
14/111
1.29
0.72–2.30
1.2875
0.7157–2.4867
Richters
68/3476
138/5347
0.76
0.57–1.02
0.7580
0.5566–1.0241
Rodriguez-Diaz
48/398
28/186
0.80
0.49–1.32
0.8014
0.4755–1.3715
Schneider
278/4878
80/931
0.66
0.51–0.86
0.6633
0.5101–0.8702
Suligoi
2/5
18/57
1.27
0.23–7.10
1.2628
0.1112–8.5647
Taylor: UK
102/180
20/59
1.67
0.95–2.93
1.6694
0.9283–3.1007
Taylor: caribbean
50/70
2/12
4.29
0.92–20.00
4.2480
0.8863–40.7423
Taylor: other
36/56
4/33
5.30
1.73–16.24
5.2451
1.6604–22.0974
Van Wagoner ≤ 25 years old
13/31
64/130
0.85
0.42–1.74
0.8524
0.3820–1.8147
Van Wagoner ≥ 26 years old
45/8
77/55
4.02
1.76–9.19
3.9905
1.6878–10.5916
Weiss: Cotonou
1/9
102/751
0.81
0.10–6.52
0.8183
0.0185–6.0119
Weiss: Yaoundé
1/7
235/644
0.39
0.05–3.20
0.3918
0.0087–3.0759
Weiss: Kisumu
161/264
41/117
1.74
1.16–2.61
1.7387
1.1418–2.6833
Weiss: Ndola
194/359
22/32
0.79
0.44–1.39
0.7863
0.4294–1.4627
Xu
146/919
323/2462
1.21
0.98–1.49
1.2109
0.9747–1.4993
Random effects summary effect:
1.1522
0.95–1.40
Heterogeneity chi-square () was 152.13 (). Brackets have infinite confidence interval replaced with value equidistant from the odds ratio as the measured confidence interval.
