Review Article
Sexually Transmitted Infections and Male Circumcision: A Systematic Review and Meta-Analysis
Table 7
Studies of the association between circumcision status and the prevalence of gonorrhea.
| | Study | Intact +ve/−ve | Circumcised +ve/−ve | Odds ratio | 95% confidence interval | Exact odds ratio | Exact confidence interval |
| | Aynaud | 1/161 | 0/48 | 0.90 | 0.04–22.47 | 0.2963 | 0.0076–[11.5518] | | Bailey | 58/118 | 55/89 | 0.80 | 0.50–1.26 | 0.7959 | 0.4892–1.2944 | | Cook | 87/453 | 175/2061 | 2.26 | 1.72–2.98 | 2.2616 | 1.6436–3.0031 | | Dave | 53/4780 | 15/967 | 0.71 | 0.40–1.27 | 0.7148 | 0.3950–1.3714 | | Diseker | 110/212 | 294/622 | 1.09 | 0.84–1.44 | 1.0977 | 0.8299–1.4474 | | Donovan | 8/107 | 19/166 | 0.65 | 0.28–1.55 | 0.6541 | 0.2388–1.6331 | | Ferris | 29/1573 | 52/2302 | 0.82 | 0.52–1.29 | 0.8162 | 0.4972–1.3164 | |
Gray et al. [44]* | 25/2177 | 3/435 | 1.67 | 0.50–5.54 | 1.6649 | 0.5046–8.6526 | |
Gray et al. [163]* | 29/2613 | 4/473 | 1.31 | 0.46–3.75 | 1.3123 | 0.4578–5.1610 | | Hand (black) | 473/250 | 71/51 | 1.36 | 0.92–2.01 | 1.3585 | 0.8987–2.0434 | | Hand (white) | 399/388 | 123/82 | 0.69 | 0.50–0.94 | 0.6858 | 0.4947–0.9474 | | Hart | 56/2920 | 48/4968 | 1.98 | 1.35–2.93 | 1.9848 | 1.3217–2.9904 | | Laumann; 1–4 partners | 9/440 | 12/542 | 0.92 | 0.39–2.21 | 0.9239 | 0.3405–2.4141 | | Laumann; 5–20 partners | 64/380 | 58/480 | 1.39 | 0.95–2.04 | 1.3934 | 0.9361–2.0775 | | Laumann; 21+ partners | 37/153 | 55/178 | 0.78 | 0.49–1.25 | 0.7831 | 0.4743–1.2826 | | Lavrey | 14/81 | 88/563 | 1.11 | 0.60–2.04 | 1.1056 | 0.5541–2.0721 | | Lloyd | 203/178 | 75/43 | 0.65 | 0.43–1.00 | 0.6544 | 0.4161–1.0203 | | Parker | 54/536 | 43/686 | 1.61 | 1.06–2.44 | 1.6067 | 1.0385–2.4983 | | Reynolds | 110/1197 | 7/184 | 2.42 | 1.11–5.27 | 2.4145 | 1.1090–6.2430 | | Richters | 85/3471 | 112/5338 | 1.17 | 0.88–1.55 | 1.1671 | 0.8669–1.5666 | | Rodriguez-Diaz | 59/387 | 28/186 | 1.01 | 0.63–1.64 | 1.0127 | 0.6122–1.7074 | | Schrek (white) | 22/130 | 10/26 | 0.44 | 0.19–1.04 | 0.4423 | 0.1750–1.1733 | | Schrek (black) | 50/73 | 19/26 | 0.94 | 0.47–1.87 | 0.9376 | 0.4447–2.0000 | | Smith | NA | NA | 1.14 | 0.92–1.41 | 1.14 | 0.92–1.41 | | Talukdar | 19/345 | 10/92 | 0.51 | 0.23–1.13 | 0.5075 | 0.2157–1.2662 | | Taylor | 72/235 | 21/83 | 1.21 | 0.70–2.09 | 1.2104 | 0.6846–2.2069 | | Wilson | 640/360 | 229/75 | 0.58 | 0.44–0.78 | 0.5825 | 0.4291–0.7847 | | Random effects summary effect: | | | | 1.0272 | 0.86–1.23 |
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Heterogeneity chi-square () was 88.81 ().
The Rakai data published in 2004 was used in calculating the summary effect odds ratio.
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