Research Article

Linear and Nonlinear QSAR Study of N2 and O6 Substituted Guanine Derivatives as Cyclin-Dependent Kinase 2 Inhibitors

Table 2

Descriptors were selected for construction of model.

No.SymbolClassMeaning

1Mor20u3D-MoRSE3D-MoRSE-signal 20/unweighted
2GATS2e2D autocorrelationGeary autocorrelation-lag 2/weighted by atomic Sanderson electronegativities
3R5pGETAWAY autocorrelation of lag 5/weighted by atomic polarizabilities
4MATS2e2D autocorrelationMoran autocorrelation-lag 2/weighted by atomic Sanderson electronegativities
5JGI6Galvez topol. ChargeMean topological charge index of order 6
6JGI4Galvez topol. ChargeMean topological charge index of order 4
7R1mGETAWAY autocorrelation of lag 5/weighted by atomic masses
8HATS0mGETAWAYLeverage-weighted autocorrelation of lag 0/weighted by atomic masses
9Mor06v3D-MoRSE3D-MoRSE-signal 20/weighted by atomic van der Waals volumes
10E1sWHIM1st component accessibility directional WHIM index/weighted by atomic electrotopological states