Hemostatic and Wound Healing Properties of Chromolaena odorata Leaf Extract
Figure 3
SWE-induced HO-1 expression. (a) Schematic diagram of human HO-1 promoter. HO-1 promoter construct was transfected into fibroblast cells, and luciferase was measured after treatment of indicated SWE (b) or single compound (c). Values are expressed as mean ± SD of four replicates. Different letters (a, b, and c) represent statistically significant difference of means compared to the values of controls and compared between groups (). (d) Western blot analysis of HO-1 expression in the presence of kinase inhibitors. Actin was used for control. The cells were pretreated with indicated kinase inhibitors for 1 h, followed by SWE treatment for 12 h. Cell lysates were subjected to Western blot.
