Clinical Study

Lipid Lowering Therapy with Combination of Niacin and Statin in Women: Age-Related Endothelial Effects

Table 1

Clinical characteristics and medications, by intervention group*.

Variables (visit)CategoryNiacin plus statin groupPlacebo plus statin group value

Age (yr)
 Mean (SD)67.73 (11.27)65.62 (6.40)0.45
 Median 68.5066.00
 Completed studyYes16 (72.73)20 (95.24)0.10
No 6 (27.27)1 (4.76)
 Relatives with CHDYes11 (55)9 (50)0.76
No9 (45)9 (50)
High blood pressure (ever told)
 Entry (visit 2)Yes15 (68.2)12 (57.1)0.45
No7 (31.8)9 (42.9)
Diabetes (ever told)
 Entry (visit 2)Yes2 (9.1)1 (5.0)1.00
No 20 (90.9)19 (95.0)
 StrokeYes2 (9.1)1 (4.76)1.00
No 20 (90.9)20 (95.24)
 SmokingCurrent1 (4.5)2 (9.52)0.24
Past7 (31.82)11 (52.38)
Never14 (63.64)8 (38.10)

Unless otherwise indicated, data are expressed as number (percentage of treatment population).
*For the niacin group , placebo group = 21, at entry. Six patients in the niacin group and 1 patient in the placebo group did not complete the study.
Yr: years; SD: standard deviation; CHD: coronary heart disease; value represents between-group comparison.