Research Article

Liraglutide Suppresses the Plasma Levels of Active and Des-Acyl Ghrelin Independently of Active Glucagon-Like Peptide-1 Levels in Mice

Figure 1

The effects of an intraperitoneal injection of liraglutide (100 μg/kg) or saline on the plasma levels of active GLP-1 (a), active ghrelin (b), and des-acyl ghrelin (c) in mice fasted for 24 h are presented. The plasma levels of active GLP-1, active ghrelin, and des-acyl ghrelin were determined 1 h after liraglutide treatment, which was administered following 24 h of food deprivation, as described in the Materials and Methods section. The data are presented as the mean ± SEM ( for each group). * .
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