Table of Contents
ISRN Gastroenterology
Volume 2013 (2013), Article ID 191729, 4 pages
http://dx.doi.org/10.1155/2013/191729
Clinical Study

Diagnostic and Therapeutic Value of ERCP in Acute Cholangitis

1Department of General Surgery, Istanbul Education and Research Hospital, 34098 Istanbul, Turkey
2Department of Gastroenterohepatology, Istanbul Education and Research Hospital, 34098 Istanbul, Turkey

Received 25 June 2013; Accepted 17 July 2013

Academic Editors: L. David and A. K. Rishi

Copyright © 2013 Kenan Buyukasik et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Cholangitis, with a clinical spectrum between acute ascending cholangitis and acute fulminant cholangitis, the mildest and the most severe forms, respectively, is the infection of bile ducts with a potential of serious mortality and morbidity. Obstruction of the bile ducts followed by infection, with E. coli being the most commonly isolated agent, is common to all forms of cholangitis. Biliary obstruction is caused by choledocholithiasis mostly. “Choledochal pressure” is the most important factor, determining morbidity. If the pressure exceeds 25 cm H2O, which is the critical value, immune dysfunction ensues. Sepsis is common if the infection of biliary ducts is suppurative. Mortality and morbidity are inevitable if left untreated or drained late. The objective of this study is, in the stand point of the current literature, to analyse the diagnostic, therapeutic success and complication rates of ERCP (Endoscopic retrograde cholangiopancreatography) in patients with a diagnosis of acute purulent cholangitis with no response to medical treatment.