Table of Contents
ISRN Radiology
Volume 2013, Article ID 235270, 7 pages
Clinical Study

Volumetric Breast Ultrasound as a Screening Modality in Mammographically Dense Breasts

Breast Cancer Research Institute, Nova Southeastern University College of Osteopathic Medicine, 5732 Canton Cove, Winter Springs, FL 32708, USA

Received 16 August 2012; Accepted 10 September 2012

Academic Editors: J.-B. Dubois and I. El Naqa

Copyright © 2013 Vincenzo Giuliano and Concetta Giuliano. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


This investigation is part of an ongoing large scale study using volumetric breast ultrasound (VBUS) as a screening modality in mammographically dense breasts, offering a substantial benefit to MR imaging of the breast in terms of cost and efficiency. The addition of VBUS to mammography in women with greater than 50% breast density resulted in the detection of 12.3 per 1,000 breast cancers, compared to 4.6 per 1,000 by mammography alone with an overall attributable risk of breast cancer of 19.92 (95% confidence level, 16.75–23.61) in our screened population. These preliminary results may justify the cost benefit of implementing the judicious use of VBUS as an alternative to MR imaging of the breast in conjunction with mammography in the dense breast screening population.