Evaluation of Serum Creatine Kinase and Urinary Myoglobin as Markers in Detecting Development of Acute Renal Failure in Severely Injured Trauma Patients

Table 2

Comparison of laboratory variables between patients with and without renal failure using t- test.

Parameters	No renal failure 𝑁=97	Renal failure 𝑁=10	𝑃-value
Hemoglobin
Day 1	10.8±2.5	10.3±2.4	0.4
Day 3	9.8±2.3	7.7±1.5	0.01
Day 5	9.8±2.1	8.4±1.04	0.08
Hematocrit
Day 1	33.9±11.4	32.13±7.5	0.6
Day 3	30.51±6.75	25.7±7.2	0.04
Day 5	31.8±8.8	25.17±3.7	0.05
TLC
Day 1	12050 (3000–38800)	9650 (6800–15500)	0.1
Day 3	9800 (1440–30600)	7500 (5200–23900)	0.4
Day 5	9600 (2500–25900)	8900 (4500–21900)	0.8
Platelet counts
Day 1	159 (40–900)	157 (80–270)	0.9
Day 3	140 (34–830)	130 (40–180)	0.8
Day 5	152.5 (58–960)	110 (40–206)	0.1
PT
Day 1	16.2 (12.7–37.9)	18.25 (15.4–19.1)	0.7
Day 3	15.75 (13.3–24.8)	17.3 (15–40.1)	<0.001
Day 5	15.25 (11.9–33.3)	17.4 (15.6–20.9)	0.6
APTT
Day 1	28.65 (20–55)	31 (21.6–66.1)	0.006
Day 3	28.4 (18.2–81.8)	31 (26.9–59.4)	0.2
Day 5	30.4 (18–136.7)	27.85 (24.9–37.7)	0.6
Na
Day 1	140.5±5.2	141.8±10.7	0.50
Day 3	140.9±8.45	151.7±12.7	<0.001
Day 5	140.0±7.8	143.3±5.3	0.28
K
Day 1	3.8±0.7	4.3±1.1	0.04
Day 3	3.5±0.8	3.9±0.8	0.21
Day 5	3.4±0.7	3.5±0.9	0.7
Ca
Day 1	8.4±1.1	7.8±1.6	0.1
Day 3	7.8±1.1	7.7±1.1	0.7
Day 5	7.6±1.3	7.9±0.7	0.5
Urea
Day 1	24 (7–76)	58 (13–240)	0.05
Day 3	26 (8–66)	64 (30–227)	0.01
Day 5	29 (8–79)	83 (33–170)	0.07
Creatinine
Day 1	0.7 (0.3–2.3)	0.7 (0.2–10.6)	0.5
Day 3	0.7 (0.3–2.8)	0.8 (0.2–8.1)	0.03
Day 5	0.5 (0.3–2.1)	0.6 (0.1–5.30)	0.03
CK
Day 1	287 (4–4730)	620 (4–16923)	<0.001
Day 3	636.5 (33–5738)	1360 (15–14345)	0.006
Day 5	416 (7–2540)	1280.5 (1–8222)	0.03