CD79B and MYD88 Mutations in Splenic Marginal Zone Lymphoma

Figure 3

The left panel illustrates the lymphoma histology of a SMZL case without mutations in CD79A, CD79B, CARD11, or MYD88. The spleen shows homogenous infiltration with small cells with abundant clear cytoplasm (H&E, 400x). The right panel illustrates the lymphoma histology case with a CD79B mutation. The spleen shows infiltration with small lymphoid cells as well as with larger immunoblast-like cells (arrows, H&E, 400x).