Research Article

Oral Lesions: Poor Markers of Virologic Failure in HIV-Infected Patients on Antiretroviral Therapy

Table 3

Factors associated with time to virologic failure among 588 patients (156 cases had missing values)1.

PredictorsBivariate analysesMultivariate analyses
Crude HR2Adj HR295% CI3 value

Race/ethnicity
 Caucasian (ref)
 African-American1.2931.3561.045–1.759
 Other0.7570.9430.343–2.594

Antiretroviral therapy naïve
 Naïve (ref)
 Experienced0.5852.2981.743–3.030

History of substance abuse
 No (ref)
 Yes1.4511.311 0.982–1.751

Affective mental health disorder
 No (ref)
 Yes1.3191.4101.078–1.843

Baseline CD4
 ≥200 cell/uL (ref)
 <200 cell/uL0.8250.7150.541–0.945

Baseline VL4
 <10,000 copies/mL (ref)
 ≥10,000 copies/mL1.3522.2821.661–3.137

1Only variables that were retained by the adjusted model were presented in this table. Variables included in the crude model: baseline OL, age, sex, race, insurance status, ART naïve/experienced, transmission risk, tobacco use, alcohol abuse, substance abuse, mental health disorder, baseline CD4, and baseline VL. 2Hazard ratios, significant association (P < 0.05). 3Confidence interval. 4VL: viral load.