Research Article

Structural Analysis of Respirasomes in Electron Transfer Pathway of Acidithiobacillus ferrooxidans: A Computer-Aided Molecular Designing Study

Figure 7

(a) The figure represents the interaction between Cyc1 and CoxB. The hydrophobic motif 145-WKWTFSY-151 essential for electron transfer is highlighted in green color. H-bonds are shown as dashed lines, heme groups of Cyc1 are represented as stick models, and CuA and CuB are shown as space fill models in red color. (b) The schematic representation of binuclear Cu center of CoxB showing the CuA coordinated by Cys222, Cys226, and His230 and CuB coordinated by Met223, His181, Cys222, and Cys226. The Cu site of CoxB plays an important role in further electron transfer to the catalytic site of CoxA. (c) The figure illustrates the interaction between heme a and heme a3 within the catalytic site of CoxA.
295718.fig.007a
(a)
295718.fig.007b
(b)
295718.fig.007c
(c)