Table of Contents
ISRN Biophysics
Volume 2013 (2013), Article ID 295718, 14 pages
http://dx.doi.org/10.1155/2013/295718
Research Article

Structural Analysis of Respirasomes in Electron Transfer Pathway of Acidithiobacillus ferrooxidans: A Computer-Aided Molecular Designing Study

BIF-Centre, Department of Bioinformatics, Orissa University of Agriculture and Technology, Bhubaneswar, Odisha 751 003, India

Received 18 June 2013; Accepted 17 July 2013

Academic Editors: O. Flomenbom, S. Taneva, and N. Weisleder

Copyright © 2013 Mahesh Chandra Patra et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Supplementary Material

The supplementary material contains hydrogen bond interactions between heme C and the residues of modelled Cyc2 within 10 Å distance from heme C; molecular interaction between RcY and Cyc1; interaction between heme groups and the amino acid ligands of Cyc1; interaction between CoxA and CoxB; interaction between Cyc1 and CoxB; and interaction between heme aa3 groups and CoxA subunit. Ramachandran plots of Cyc2 and CoxA models has been provided depicting more than 90% of residues of both proteins within allowed region of the plots. The predicted Z-scores of modeled Cyc2 and CoxA subunits has been provided as two dimensional plots with central black spots indicating Z-scores of the query protein with respect to that of the solved proteins available in PDB. The predicted secondary structure of Cyc2 protein has been shown. Hydropathy analysis is shown indicating Cyc2 protein does not contain potential transmembrane regions. The graphical representation of intermolecular interaction between heme C and the surrounding residues has been illustrated.

  1. Supplementary Materials