Building Spinal and Brain Commissures: Axon Guidance at the Midline
Figure 4
Guideposts and guidance signaling controlling the corpus callosum formation. (a) Axons from the cingulate cortex (in orange) pioneer the corpus callosum. Neocortical callosal axons (in red) turn medially and navigate towards the midline. The axons are guided by cues emanating from various sources, the midline glia, migrating neurons, and meninges. (b) Summary of the major guidance cues guiding the callosal axons across the midline.
