Research Article

Sentinel Lymph Node Biopsy in Patients with Thick Primary Cutaneous Melanoma: Patterns of Use and Underuse Utilizing a Population-Based Model

Table 1

Patient and tumor characteristics of 1,991 patients with thick primary cutaneous melanoma according to whether or not they received a sentinel lymph node biopsy (SLNB).

VariableSLNB,
N = 1,158 (%)
No SLNB,
N = 833 (%)
P value

Age, years
 1 to 3997 (8.4)21 (2.5)<0.001
 40 to 49135 (11.7)43 (5.2)
 50 to 59239 (20.6)65 (7.8)
 60 to 69243 (21)97 (11.6)
 70 to 79268 (23.1)192 (23.1)
 80 or more176 (15.2)415 (49.8)
Sex
 Female416 (35.9)525 (63)=0.631
 Male742 (64.1)308 (37)
Race/ethnicity
 Asian22 (1.9)8 (1)=0.062
 Black13 (1.1)14 (1.7)
 Hispanic55 (4.8)30 (3.6)
 Native American6 (0.5)1 (0.1)
 Unknown6 (0.5)10 (1.2)
 White1,056 (91.2)770 (92.4)
Mean Breslow depth
(mm)
6.836.35<0.001
Tumor histology
 Acral lentiginous58 (5)26 (3.1)=0.053
 Amelanotic33 (2.9)19 (2.3)
 Desmoplastic225 (19.4) 160 (19.2)
 Epidermoid28 (2.4)16 (1.9)
 Lentigo maligna16 (1.4)23 (2.8)
 Nevus associated7 (0.6)4 (0.5)
 Nodular606 (52.3)463 (55.6)
 Regressing9 (0.8)1 (0.1)
 Superficial Spreading176 (15.2)121 (14.5)
Tumor location
 Arm301 (26)202 (24.3)<0.001
 Head/neck261 (22.5)315 (37.8)
 Leg226 (19.5)114 (13.7)
 Trunk368 (31.8)194 (23.3)
 Overlapping/other2 (0.2)8 (1)
Tumor ulceration
 No501 (43.3)356 (42.7)=0.857
 Yes632 (54.6)456 (54.7)
 Unknown25 (2.2)21 (2.5)