Glomerular Disease in Patients with Infectious Processes Developing Antineutrophil Cytoplasmic Antibodies
Pauci-immune glomerulonephritis and acute interstitial nephritis in a patient with ANCA triggered by infectious endocarditis. (a) Normal appearing glomerulus without endocapillary or mesangial proliferation (PAS; 400x). (b) Glomerulus with area of segmental scarring: nonscarred portion of tuft appears to be within normal limits (PAS; 400x). (c) Glomerulus with crescent formation (PAS; 400x). (d) Tubulointerstitial inflammation (PAS; 400x). (e)–(EM): Portion of tuft without significant electron densities, and without endocapillary or mesangial hypercellularity (5000x).