International Scholarly Research Notices / 2013 / Article / Tab 6

Review Article

Glomerular Disease in Patients with Infectious Processes Developing Antineutrophil Cytoplasmic Antibodies

Table 6

Histological types of glomerular disease, serum complement levels, and ANCA specificity in 50 patients with infections, ANCA positivity, and glomerular disease.

Histological diagnosisNumber of patientsPercent of patientsLow serum complementc-ANCA and/or PR3p-ANCA and/or MPOOther or Nonidentified ANCA

Pauci-immune GN,
vasculitis
23455/10 (38%)5/23 (22%)8/23 (35%)10/23 (43%)
Postinfectious GN193815/17 (88%)19/19 (100%)1/19 (5%)0
Anti-GMB GN150001 (100%)
Interstitial nephritis5104/5 (80%)2/5 (40%)3/5 (60%)0
Acute tubular necrosis482/3 (67%)2/4 (50%)2/4 (25%)1/4 (25%)
Other histology1221/1 (100%)1/2 (50%)1/2 (50%)
Nonidentified GN27123/3 (100%)4/7 (57%)4/7 (57%)0

GN: glomerulonephritis, GBM: glomerular basement membrane. 1One each, focal glomerulosclerosis, chronic sclerosing glomerulonephritis. 2Immunofluorescence and electron microscopy findings were not reported. The differentiation between pauci-immune and postinfectious glomerulonephritis was not feasible from only the light microscopy picture.