High-Performance Liquid Chromatographic Method for Analysis of Emtricitabine in Rat Plasma: Method Development, Validation and Application to a Pharmacokinetic Study

Table 1

Intra-day and inter-day precision and accuracy of emtricitabine in rat plasma (𝑛=6).

Concentration (µg mL^−1)	Observed concentration; (µg mL^−1)	Precision%	Accuracy%
Intraday
0.1	0.097 ± 0.003	3.09	97.0
1.0	0.982 ± 0.044	4.48	98.20
2.5	2.465 ± 0.078	3.16	98.0
Interday
0.1	0.092 ± 0.005	5.45	92.0
1.0	0.975 ± 0.063	6.46	97.50
2.5	2.427 ± 0.105	4.32	97.08