Stability-Indicating Validated Novel RP-HPLC Method for Simultaneous Estimation of Methylparaben, Ketoconazole, and Mometasone Furoate in Topical Pharmaceutical Dosage Formulation
Table 4
Accuracy results for MP, KT, and MF.
Active components
Amount added (g/mL)
Amount recovered (g/mL)
% Recovery# ± SD; % RSD*
MP
5.05
5.11
101.1 ± 0.17; 0.17
10.10
10.19
100.9 ± 0.63; 0.62
15.15
15.14
99.9 ± 0.12; 0.12
KT
49.8
50.37
101.1 ± 0.05; 0.05
99.6
100.41
100.8 ± 0.25; 0.25
149.4
149.63
100.2 ± 0.13; 0.13
MF
2.53
2.54
100.8 ± 0.62; 0.62
5.05
5.06
99.9 ± 0.36; 0.36
7.58
7.57
99.9 ± 0.48; 0.48
Determined on three values. #Mean of three determinations.
