CD133 Staining Detects Acute Kidney Injury and Differentiates Clear Cell Papillary Renal Cell Carcinoma from Other Renal Tumors

Figure 2

CD133 expression in varying degrees of renal tubular injury. Under normal circumstances, only focal CD133 positive cells were noted in renal tubules (a). With injury, tubular expression of CD133 can demonstrate mild to severe upregulation (mild, (b); moderate, (c); severe, (d)) (magnification ×400, (a)–(d)).

(a) Normal (rare CD133 expression)

(b) Mild tubular injury (CD133, 1+)

(c) Moderate tubular injury (CD133, 2+)

(d) Severe tubular injury (CD133, 3+)