A Stability Indicating Assay Method Development and Validation for the Frovatriptan Succinate Monohydrate by Using UV: A Spectrophotometric Technique

Table 1

Accuracy data of developed method for analysis of FSM in various media (𝑛=3).

Media	Levels	Storage conditions
		Freeze (5°C ± 0.5°C)			Room (25°C ± 0.5°C)
		Absorbance (±SD)	RSD (%)	Recovery (%)	Absorbance (±SD)	RSD (%)	Recovery (%)
Distilled water	LC	0.351±0.001	0.285	103.931	0.352±0.003	0.714	104.320
	IC	0.441±0.003	0.600	104.112	0.437±0.004	0.804	103.102
	HC	0.514±0.003	0.625	100.997	0.520±0.003	0.484	102.161
Phosphate buffer (pH 6.7)	LC	0.388±0.002	0.536	100.139	0.382±0.004	0.944	97.460
	IC	0.475±0.004	0.740	98.154	0.475±0.004	0.740	97.580
	HC	0.578±0.003	0.556	99.849	0.578±0.003	0.612	97.425
Acetate buffer (pH 5.5)	LC	0.374±0.003	0.706	98.289	0.364±0.001	0.275	96.313
	IC	0.480±0.006	1.163	99.404	0.471±0.004	0.925	99.756
	HC	0.554±0.007	1.212	98.275	0.567±0.006	1.003	100.047