Comparative Effects of Phosphoenolpyruvate, a Glycolytic Intermediate, as an Organ Preservation Agent with Glucose and N-Acetylcysteine against Organ Damage during Cold Storage of Mouse Liver and Kidney
Effects of PEP, glucose, or NAC on mouse liver damage during cold preservation. (a) Changes in LDH concentrations in the preservation solutions; PBS , PBS + 100 mM PEP , PBS + 100 mM glucose , and PBS + 10 mM NAC . Each bar represents the mean SEM. * and **, compared with the PBS group. #, compared with the PBS + 100 mM PEP group. (b) Histological pictures of the liver 72 h after cold preservation. The liver tissues were fixed with 10% buffered formalin, embedded in paraffin, sectioned, and stained with hematoxylin-eosin. Nonpreserved fresh liver served as a control. Scale bar μm.
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