Comparative Effects of Phosphoenolpyruvate, a Glycolytic Intermediate, as an Organ Preservation Agent with Glucose and N-Acetylcysteine against Organ Damage during Cold Storage of Mouse Liver and Kidney
Effects of PEP on mouse kidney damage during cold preservation. (a) Changes in LDH concentrations in the preservation solutions; PBS , PBS + 1 mM PEP , + 10 mM PEP , and + 100 mM PEP . Each bar represents the mean SEM. * and **, compared with the PBS group. (b) Histological pictures of the kidney 72 h after cold preservation. The liver tissues were fixed with 10% buffered formalin, embedded in paraffin, sectioned, and stained with hematoxylin-eosin. Nonpreserved fresh kidney served as a control. Scale bar μm.
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