Table of Contents
ISRN Infectious Diseases
Volume 2013 (2013), Article ID 387961, 5 pages
Clinical Study

Prevalence of HPV in Adolescents Virgins and Sexually Active at a University Hospital in the City of Rio de Janeiro, Brazil

1State University of Rio de Janeiro, Rio de Janeiro, Brazil
2Hospital Servidores of the State of Rio de Janeiro, Rio de Janeiro, Brazil
3Hospital Universitário Pedro Ernesto (HUPE), Rio de Janeiro, Brazil
4Eleuterio Laboratory, Fortaleza, Brazil
5Federal University of Ceará, Fortaleza, Brazil

Received 20 May 2013; Accepted 18 June 2013

Academic Editors: J.-M. Bart and M. Pourshafie

Copyright © 2013 Renata Mírian Nunes Eleutério et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Sexually transmitted diseases (STDs) are common worldwide, with especially alarming numbers in Brazil. Among the most common infections is human papillomavirus (HPV). The possibility of the nonsexual transmission of HPV is not well defined and is the subject of debate. This study aimed to identify the prevalence of HPV in adolescents with no history of sexual intercourse compared with a group of similar age with sexual activity. 100 adolescents were evaluated with at least two years after menarche, who attended from January 2007 to January 2009 at the University Hospital Pedro Ernesto, Rio de Janeiro, Brazil. Among the adolescents, 50 had intact hymen and 50 reported regular sexual activity. For patients without sexual intercourse (group 1) we collected material from vestibule and for patients with sexual activity (group 2) we collected material from vagina and endocervix. The search for HPV-DNA 2nd generation hybrid capture (hC2) was performed. In group 1 the test was positive in 3 cases (6%). In the second group, 33 cases (66%) were positive for at least one site. The positivity in girls with sexual activity is high. On the other hand, the HPV infection, although rare, may occur in girls without sexual intercourse.