The P25 Ookinete Surface Proteins: Homology Modeling and Phylogenetic Relationships
Figure 7
(a) Electrostatic molecular surface representation of the models of P25 proteins: front view. (b) Electrostatic molecular surface representation of the models of P25 proteins: opposite view. (c) Electrostatic molecular surface representation of the models of P25 proteins: edge I. (d) Electrostatic molecular surface representation of the models of P25 proteins: edge II. (e) Electrostatic molecular surface representation of the models of P25 proteins: edge III. Electrostatic molecular surface representation of the models of transmission blocking surface proteins of P25 family was prepared with the help of GRASP software. Surface potential was taken from −10kT (red) to +10kT (blue). Figure (a) represents the front view of P28 proteins, (b) the opposite face after 180° rotation, and ((c)–(e)) the view of each edge of the molecule. ProsaWeb, PROCHECK, and WhatIF programs were used for statistical evaluation of the final models. As represented by the different views of the molecule, all the 8 members of P25 family have very different charge distribution. Most of them are negatively charged overall.
