Blood Pressure Variability: Prognostic Value and Therapeutic Implications

<table class="table-group" id="tab3"><tr><td><table class="table"><tr><td class="thead-hr" colspan="2"><hr/></td></tr><tr class="thead"><td align="left">Tissue</td><td align="left">Alterations</td></tr><tr><td class="thead-hr" colspan="2"><hr/></td></tr><tr><td align="left">Heart </td><td align="left">Late left ventricular hypertrophy <br/>Impairment of diastolic function in both left and right ventricle <br/>Increase cardiac expression of type I and III collagen <br/>Interstitial fibrosis and wall thickening </td></tr><tr><td align="left" colspan="2"><hr/></td></tr><tr><td align="left">Vessels</td><td align="left">Aortic hypertrophy <br/>Increase in wall thickness <br/>Collagen accumulation <br/>Smooth muscle cell growth <br/>Impaired arterial distensibility</td></tr><tr><td align="left" colspan="2"><hr/></td></tr><tr><td align="left">Kidney</td><td align="left">Increase in mesangial matrix <br/>Glomerular collapse <br/>Fibrohyalinosis <br/>Thickening of basement membrane of Bowman’s capsule</td></tr><tr class="table-tr"><td colspan="2"><hr class="tbody-hr"/></td></tr></table></td></tr></table>

Target organ damage in chronic sinoaortic denervated rats.

International Scholarly Research Notices

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Table 3

Table 3: Blood Pressure Variability: Prognostic Value and Therapeutic Implications 