Serum Levels of Interleukin-6 and Interleukin-10 as Biomarkers for Hepatocellular Carcinoma in Egyptian Patients

Table 3

Diagnostic values of AFP, IL-6, and IL-10 for the detection of HCC.

	Cutoff value	AUC	Sensitivity	Specificity	Accuracy	+LR	−LR	PPV	NPV
AFP	>20 ng/mL	0.76	80	80	80%	4	0.25	57.1	92.3
IL-6	>8.6 pg/mL	0.93	90	86.67	87.5%	6.75	0.12	69.2	96.3
IL-10	>9.7 pg/mL	0.91	80	96.67	92.5%	24	0.21	88.9	93.5

+LR: positive likelihood ratio.
−LR: negative likelihood ratio.
PPV: positive predictive value.
NPV: negative predictive value.