Endocytic Adaptor Protein Epsin Is Elevated in Prostate Cancer and Required for Cancer Progression
Figure 2
Expression of epsins 1 and 2 is increased in prostate tumor compared to normal prostate tissues in mice. (a) Protein levels of epsins 1 and 2 in the indicated normal mouse prostate or TRAMP prostate tumor tissues, as well as normal prostate epithelial cells and TRAMP C1 cells, were analyzed by western blotting. (b) IHC staining for epsin 1 in normal prostate and prostate tumor from TRAMP mice. Arrows indicate prostate cancer cells with upregulated epsin 1 protein expression. (c) qRT-PCR revealed increased expression of epsins 1 and 2 in normal (N) and prostate tumor (T) samples from TRAMP mice. per group in all panels. *indicates value <0.05.
