Research Article
Microsatellite Instability in Head and Neck Squamous Cell Carcinoma: A Study of a Brazilian Population
Table 3
D3S1611 MSI frequency according to clinical and epidemiological features.
| Features | D3S1611 marker | Total | MSI | MSS | P | No. | (%) | No. | f | No. | f |
| Gender | | | | | | | | Female | 8 | (21.6) | 1 | 0.125 | 7 | 0.875 | — | Male | 29 | (78.4) | 4 | 0.138 | 25 | 0.862 | | Age range, yrs | | | | | | | | ≤50 | 8 | (21.6) | 0 | 0.0 | 8 | 1.0 | 0.034 | 50–70 | 22 | (59.5) | 2 | 0.091 | 20 | 0.909 | | >70 | 7 | (18.9) | 3 | 0.492 | 4 | 0.508 | | Tumor site | | | | | | | | Oral cavity | 15 | (40.5) | 1 | 0.067 | 14 | 0.933 | — | Oropharynx | 8 | (21.6) | 3 | 0.375 | 5 | 0.625 | | Larynx | 14 | (37.9) | 1 | 0.071 | 13 | 0.929 | | Differentiation | | | | | | | | Well | 8 | (21.6) | 0 | 0.0 | 8 | 1.0 | 0.339 | Moderately | 21 | (56.8) | 3 | 0.143 | 18 | 0.857 | | Poorly | 8 | (21.6) | 2 | 0.250 | 6 | 0.750 | |
| Total | 37 | (100.0) | 5 | 0.135 | 32 | 0.865 | |
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MSI: microsatellite instability; MSS: microsatellite stable; f: frequency; P: significance value.
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