Research Article

Evaluation of Artemisia amygdalina D. for Anti-Inflammatory and Immunomodulatory Potential

Table 3

Effect of different extracts of Artemisia amygdalina D. on delayed-type hypersensitivity response in mice (mean ± SE) ( ).

DTH assay

GroupsDose (mg/kg)24 hr paw thickness (mm)48 hr paw thickness (mm)

ControlSRBC0.6825 ± 0.04a0.335 ± 0.021a
Methanolic fraction1000.2575 ± 0.02c0.105 ± 0.012d
Ethyl acetate fraction1000.386 ± 0.04bc0.21 ± 0.023c
Petroleum ether fraction1000.52 ± 0.04b0.306 ± 0.021b
Aqueous fraction1000.368 ± 0.032c0.222 ± 0.027c
Cyclophosphamide500.292 ± 0.032c0.078 ± 0.006d

Values along the same column with different superscripts are statistically significant to each other using Tukey’s HSD test ( ).