Research Article

Relationship between Birth Weight and Metabolic Status in Obese Adolescents

Table 1

Subject characteristics (mean ± S.E.M, [range]).

Age (years)13.5 ± 0.2 (9.8–16.9)
Birth weight (g)3527 ± 64 (1899–4990)
BMI33.0 ± 0.6 (21.8–46.1)
BMI z-score2.22 ± 0.04 (1.18–3.00)
Systolic BP z-score0.30 ± 0.08 (−1.71–3.24)
Diastolic BP z-score0.33 ± 0.10 (−2.41–3.09)
PAT (RH-PAT)1.77 ± 0.04 (1.00–2.73)
FPG (Mmol/L)4.93 ± 0.05 (3.00–6.00)
2 h GTT glucose (mmol/L)5.59 ± 0.15 (2.80–9.80)
Insulin (pmol/L)18.3 ± 1.11 (2.0–51.0)
HOMA4.08 ± 0.26 (0.35–12.69)
HDL cholesterol (mmol/L)1.16 ± 0.03 (0.62–2.57)
LDL cholesterol (mmol/L)2.36 ± 0.07 (0.69–4.35)
Triglycerides (mmol/L)1.19 ± 0.07 (0.30–4.20)
Leptin (ng/mL)38.8 ± 1.75 (9.32–86.20)
Adiponectin (μg/mL)2.49 ± 0.13 (0.68–7.20)
Leptin/adiponectin ratio19.6 ± 1.2 (3.0–53.0)
A1C (%)5.4 ± 0.1 (4.7–6.0)
Body fat (percent)45.5 ± 0.1 (35.5–56.3)

Values show median and range. BMI: body mass index; BP: blood pressure, PAT: peripheral arterial tomography; HOMA: Homeostasis Model Assessment. A normal distribution of values for each variable was confirmed using the Kolgomorov-Smirnov test. Values were obtained from 95 individuals, except for values for A1C and percent body fat, which were obtained from a sub-group of 69 subjects. The mean age, BMI z-score, and birth weight of this sub-group did not significantly differ from the larger cohort.