Table of Contents
ISRN Obesity
Volume 2013, Article ID 506751, 5 pages
Research Article

Normal Weight Estonian Prepubertal Boys Show a More Cardiovascular-Risk-Associated Adipose Tissue Distribution than Austrian Counterparts

1Center of Molecular Medicine, Institute of Pathophysiology and Immunology, Medical University of Graz, Heinrichstraße 31a, 8010 Graz, Austria
2Center of Physiological Medicine, Institute of Physiological Chemistry, University of Graz, 8010 Graz, Austria
3Faculty of Exercise and Sports Sciences, Center of Behavioural and Health Sciences, University of Tartu, 50090 Tartu, Estonia
4Department of Pediatrics, Paracelsus Private Medical University of Salzburg, 5020 Salzburg, Austria
5Practice for General Internal Medicine, Bruck a.d.M., 8600 Graze, Austria
6Clinical Institute for Medical and Chemical Laboratory Diagnosis, Medical University of Graz, 8010 Graz, Austria

Received 4 December 2012; Accepted 21 December 2012

Academic Editors: J. J. Gleysteen, H. Gordish-Dressman, and D. Micic

Copyright © 2013 Sandra J. Wallner-Liebmann et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Objective. Risk phenotypes for cardiovascular disease (CVD) differ markedly between countries, like the reported high difference in CVD mortality in Austria and Estonia. Hitherto, the goal of this study was to find out risk profiles in body fat distribution yet present in childhood, paving the way for later clinical end points. Methods. he subcutaneous adipose tissue (SAT) distribution patterns in 553 Austrian (A) and Estonian (E) clinically healthy normal weight boys aged 11.1 (±0.8) years were analysed. We applied the patented optical device Lipometer which determines the individual subcutaneous adipose tissue topography (SAT-Top). Results. Total body fat did not differ significantly between E and A boys. A discriminant analysis using all Lipometer data, BMI, and the total body fat (TBF) yielded 84.6% of the boys correctly classified in Estonians and Austrians by 9 body sites. A factor analysis identified the SAT distribution of E as critically similar to male adult patients with coronary heart disease (CHD). Conclusions. We show in normal weight Estonian boys a highly significant decreased fat accumulation on the lower body site compared to age matched Austrian males. This SAT-Top phenotype may play an important role for the increased cardiovascular risk seen in the Estonian population.