Table of Contents
ISRN Vascular Medicine
Volume 2013 (2013), Article ID 507637, 9 pages
http://dx.doi.org/10.1155/2013/507637
Clinical Study

Associations between Pulse Wave Velocity, Aortic Vascular Calcification, and Bone Mineral Density in Chronic Hemodialysis Patients and General Population

1Department of Internal Medicine and Hemodialysis, Clinical Hospital, Partizanska BB, 7000 Bitola, Macedonia
2Deutsches Rotes Kreuz, Rohrborner, 99610 Sömmerda, Germany
3Department of Statistics, Faculty of Economics, Marksova BB, 7500 Prilep, Macedonia
4University Hospital of Nephrology, Medical Faculty, Ss. Cyril and Methodius University in Skopje, 1000 Skopje, Macedonia

Received 27 November 2012; Accepted 24 December 2012

Academic Editors: A. Hirata and A. Suzuki

Copyright © 2013 P. Avramovski et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

The aims of this study were to compare PWV, vascular calcification (VC), and bone mineral density (BMD) in chronic hemodialysis patients (CHP) with those of the general population patients (GPP). We evaluated 60 GPP (aged ) compared with 80 CHP (aged ). PWV was determined from time diversity propagation of the carotid and femoral artery by Doppler ultrasound. Lateral lumbar radiography (LLR) of the abdominal aorta was used to determine the overall abdominal aortic calcification (AAC) score. BMD of the hip and the spine was assessed by dual energy X-ray absorptiometry (DEXA). Biochemical parameters (PTH, Ca2+, P, albumin, CRP, etc.) were determined in all participants according to standard laboratory procedures. The mean PWV was  m/s in the GPP and  m/s in the CHP. The mean AAC score was as follows: GPP: , CHP: . The mean BMD at hip was as follow: GPP:  (g/cm2), CHP:  (g/cm2). In the GPP, PWV correlate with VC ( ), BMD ( ), albumin ( ), and CRP ( ). In the CHP, PWV correlates with VC ( ), BMD ( ), albumin ( ), and CRP ( ). There is a strong inverse correlation between PWV and BMD and between VC and BMD. There is a positive correlation between PWV and VC.